Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa

Yazarlar

  • Nasri Meriem Laboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria. Algeria https://orcid.org/0000-0001-7536-865X
  • Touati Noureddine Laboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria. https://orcid.org/0000-0002-1110-6770
  • Abed Hanane Laboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria. https://orcid.org/0000-0001-7852-0653

DOI:

https://doi.org/10.24925/turjaf.v11i6.1106-1109.5984

Anahtar Kelimeler:

Ethanol extract- Citrus deliciosa- antioxidant activity- acute toxicity- flavonoids.

Özet

Our phytochemical study focused on the leaves of Citrus deliciosa of Algerian origin, in order to evaluate its antioxidant activity and its acute toxicity, using scavenger activity of DPPH radicals, ABTS and acute toxicity. The ethanol extract of Citrus deliciosa contains 85.62 ± 2.24 μg /mg dried matter and 3.02 ± 0.17 μg/mg dried matter. The antioxidant activity was confirmed against the DPPH radical (IC50 = 252.07 ± 0.02 μg /mL) and ABTS (IC50 = 398.26 ± 0.01 μg /mL). No mortality or abnormal behavior was observed in mice at oral doses less of 1600 mg/kg. According to the results obtained, Citrus deliciosa leaves exhibit significant antioxidant activity and are safe at levels lower than 1600 mg/kg B.W., which supports their application in phytotherapy, pharmaceutical biotechnology, and the food sector for therapeutic or preventive purposes.

Yazar Biyografisi

Nasri Meriem, Laboratory of Health and Environment, Faculty of Nature and Life Sciences, University of Mohamed El Bachir El Ibrahimi (UMBI), Bordj Bou Arreridj 34000, Algeria. Algeria

biology department

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Yayınlanmış

2023-06-30

Nasıl Atıf Yapılır

Meriem, N., Noureddine, T., & Hanane, A. (2023). Acute Toxicity and Antioxidant Activity of Algerian Citrus deliciosa. Türk Tarım - Gıda Bilim Ve Teknoloji Dergisi, 11(6), 1106–1109. https://doi.org/10.24925/turjaf.v11i6.1106-1109.5984

Sayı

Bölüm

Araştırma Makalesi