Evaluation of the Blood Gas Parameters Changes During Ovariohysterectomy with Butorphanol, Medetomidine, and Ketamine Combination Anesthesia in Queens

Abstract

The aim of this study was to determine the effect of anesthesia with a combination of butorphanol, medetomidine and ketamine on blood gas parameters during ovariohysterectomy in queens. Nineteen queens of different breeds, between 6 and 72 months of age, which were neutered, were used in the study. Before anesthesia, 1 mL of blood was taken from Vena cephalica antebrachi to a heparinized syringe and blood gas parameters were evaluated. Queens determined to be healthy as a result of clinical examination and laboratory analyzes were taken under general anesthesia for ovariohysterectomy. Butorphanol (0.01 mg/kg, IV) was administered for anesthesia induction, medetomidine (0.08 mL/kg, IV) was administered 5 minutes after following the induction and ketamine (5-7.5 mg/kg, IV) was administered intravenously 10 minutes later. At the 10th minute of ketamine administration, blood samples were taken from the queens again. Blood gas parameters such as pH, pCO2, pO2, sO2, Na, Ca, K, Cl, Glu, Lac, BE and HCO3 were evaluated in blood samples taken before and during anesthesia. It was determined that pH, pO2, sO2, BE and HCO3 levels were lower and pCO2 and lactate concentrations were higher in anesthesia-induced queens compared to pre-anesthesia. As a result, it was thought that monitoring blood gas parameters in queens undergoing ovariohysterectomy may be useful to prevent complications that may occur before and after the operation.